Tutorial: Creating a patient friendly ODT

With both pediatric and aging populations increasingly suffering from the inability to swallow, a melting, pleasantly tasting, and memorable formulation is exactly what they are looking for. Orally disintegrating tablets have steadily increased in popularity for many reasons, one being the efficient manufacturing methods of preparation and the overall patient centricity. Made often by direct compression, ODTs are usually small porous tablets and often include taste-masked APIs. In spite of many advantages, ODTs have their limitations in size, shape, API loading, hardness, and meeting its goals for disintegration and friability. Here we highlighted the formulation of a small ODT and addressed the challenges and possible solutions.